Tailored Therapy Based on Molecular Characteristics in Endometrial Cancer

Molecular markers in gastrointestinal cancer: targeted therapy and tailored chemotherapy.

Molecular therapy as a future strategy in endometrial cancer.

Of all gynecologic cancers, endometrial cancer is the most common cancer in the US and Europe. In addition, it is presently the second most common gynecologic cancer in the world. As a result of increasing menopausal, obese and tamoxifen use women, the incidence of the cancer seems to be on the increase. Surgery is the major treatment, whereas postoperative radiation therapy in high-intermediat...

Emerging concept of tailored lymphadenectomy in endometrial cancer

Molecular mechanisms involved in multidrug resistance in breast cancer therapy

Breast cancer is the most prevalent cancer in women. Chemotherapy is the main strategy in the treatment of this disease especially in the advanced form of the disease. Despite the recent progress in the development of new chemotherapy, the effectiveness of these drugs has dramatically reduced due to multidrug resistance. The phenotype of multidrug resistance (MDR) can occur through different me...

Tailored hormonal therapy in secretory adrenocortical cancer.

Tailored hormonal therapy in secretory adrenocortical cancer Mitotane is often considered the front-line hormonal therapy of adrenocortical carcinoma (ACC). An illustrative case concerning this issue and the rationale to ponder other alternatives is reported. A 69 year-old woman, diagnosed with ACC was admitted with hypertensive crisis, supraventricular tachycardia, congestive heart-failure, di...